Retinol chosen by dermatologists. Now taken a step further

In skincare, retinol has long been called “the gold standard of anti-aging.”

But behind its celebrated title, two constant challenges remained: its impressive power, and the irritation and instability that often followed.

“Can we push the results even further,
while making the experience gentler?”

Generations of retinoids have tried to answer this question, but each fell short in its own way.
First-generation retinol delivered strong results but was often too harsh.
Second-generation retinal was gentler but struggled to create the firmness people expected.
Third-generation retinoic acid derivatives found a better balance, but still couldn’t be considered a true breakthrough.

The next generation: Dermatinol™

A new evolution built on next-generation HPR.

That question led to the creation of Dermatinol™, a proprietary, stabilized retinoid developed in the Dr.Oracle research lab.

Dermatinol™ is built on the strengths of fourth-generation HPR (HydroxyPinacolone Retinoate), a retinol recognized for advanced performance.
Using our proprietary stabilization and delivery technology, we addressed HPR’s known weaknesses: instability, limited absorption, and irritation potential.

The result is a low-irritation, high-efficacy retinol designed to meet dermatologists’ clinical standards.

A retinol you can use every day. Comfortably and confidently.

Dermatinol™ absorbs easily, feels comfortable on the skin, and maintains strong wrinkle- and firmness-improving benefits. Even sensitive skin and first-time retinol users can incorporate it into a daily routine with confidence.

With consistent use, your skin feels calmer, and the results grow more visible.

Now, the level of retinol care once limited to dermatology clinics becomes part of your everyday ritual.

The evolution of retinol by dermatologists, Dermatinol™

Stronger and firmer skin with each day.